検査項目解説
| 検査名 | ヘモグロビンA2 |
| 英検査名 | Hemoglobin A2 |
| 検体基準範囲 |
採血後速やかに測定するか、冷蔵保存し、24時間以内に測定する。 血液 |
| 測定法 | |
| 基準範囲出典 |
1.The Management of Sickle Cell Disease. Fourth edition. Bethesda, MD: National Institutes of Health. National Heart, Lung, and Body Institute, 2002 2.Rosse WF, Telen M, Ware R: Transfusion Support for Patients with Sickle Cell Disease. Bethesda, MD: American Association of Blood Banks 1998 3.Ferster A, Tahriri P, Vermylen C, et al: Five years of experience with hydroxyurea in children and young adults with sickle cell disease. Blood 2001;97:3268-3632 4.Charache S, Terrin ML, Moore RD, et al: Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. N Engl J Med 1995;332:1317-1322 5.Sebia CapillaryS Manual: 2014(06) Available at www.iproweb.fr/test/3%20-%20AU%20SOL/SEBIA%20-%20CAPILLARYS%202/MANUAL%202.pdf 6.Keren DF, Shalhoub R, Gulbranson R, et al: Expression of hemoglobin variant migration by capillary electrophoresis relative to hemoglobin A2 improves precision. Am J Clin Pathol 2012 Apr;137(4):660-664 |
| 解説 |
HbA2は正常成人の血色素の一部分(1.2～3.5%)を占めるヘモグロビンで、α鎖2個とδ鎖2個の四量体からできている。 高値（血液）：β-サラセミア、鎌状赤血球形質 |